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KREMEN2 Antibody (Center) (Cat. #P31211) western blot analysis in ZR-75-1,K562,NCI-H460 cell line lysates (35ug/lane).This demonstrates the KREMEN2 antibody detected the KREMEN2 protein (arrow).

Rabbit Polyclonal Antibody to KREMEN2

货号：
P31211
别名：
Kremen protein 2, Dickkopf receptor 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KREMEN2, KRM2
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q8NCW0
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to KREMEN2

Description
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Description

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Specification
Aliases	Kremen protein 2, Dickkopf receptor 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KREMEN2, KRM2
Entrez GeneID	79412
Swissprot	Q8NCW0
WB Predicted band size	48.8kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.