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DIAPH3 Antibody (C-term) (Cat. #P31665) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DIAPH3 antibody detected the DIAPH3 protein (arrow).

Rabbit Polyclonal Antibody to DIAPH3

  • 货号:

    P31665
  • 别名:

    Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, MDia2, DIAPH3, DIAP3
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9NSV4
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to DIAPH3

Description

DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Specification

Aliases Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, MDia2, DIAPH3, DIAP3
Entrez GeneID 81624
Swissprot Q9NSV4
WB Predicted band size 136.9kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P31665

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