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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using EIF2AK2 mouse mAb against A431 (1), MCF-7 (2), PC-12 (3) cell lysate.
Flow cytometric analysis of A431 cells using EIF2AK2 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to EIF2AK2
-
货号：
30664 -
别名：
PKR; PRKR; EIF2AK1 -
应用：
WB,FCM -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P19525 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Mouse Monoclonal Antibody to EIF2AK2
Description |
|---|
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. |
References |
|---|
| 1. J Alzheimers Dis. 2010;21(4):1217-31. 2. Mol Cells. 2011 Aug;32(2):167-72. |
Specification |
|
|---|---|
| Aliases | PKR; PRKR; EIF2AK1 |
| Entrez GeneID | 5610 |
| Swissprot | P19525 |
| clone | 3A10F7 |
| WB Predicted band size | 62kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Western blot analysis using EIF2AK2 mouse mAb against A431 (1), MCF-7 (2), PC-12 (3) cell lysate.
- Flow cytometric analysis of A431 cells using EIF2AK2 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30664
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