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Rabbit Polyclonal Antibody to PCSK5
-
货号:
P02954 -
别名:
PC5; PC6; PC6A; SPC6 -
应用:
IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
Q92824 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to PCSK5
Description |
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This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B). |
Specification |
|
---|---|
Aliases | PC5; PC6; PC6A; SPC6 |
Swissprot | Q92824 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human PCSK5 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P02954

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