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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HepG2 cell, Mouse brain tissue lysates, Primary antibody: P03317(ITM2C Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
Rabbit Polyclonal Antibody to ITM2C
-
货号：
P03317 -
别名：
E25; BRI3; E25C; ITM3; BRICD2C -
应用：
WB -
反应种属：
Human, Mouse -
抗体类型：
Primary antibody -
Swissprot：
Q9NQX7 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to ITM2C
Description |
|---|
Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Specification |
|
|---|---|
| Aliases | E25; BRI3; E25C; ITM3; BRICD2C |
| Swissprot | Q9NQX7 |
| WB Predicted band size | 30 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ITM2C |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/5000-1/10000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P03317
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