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Mouse Monoclonal Antibody to FGFR3
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货号:
30821 -
别名:
ACH; CEK2; JTK4; CD333; HSFGFR3EX -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P22607 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to FGFR3
Description |
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This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
References |
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1.Mol Cancer. 2013 Jul 31;12:83. |
Specification |
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Aliases | ACH; CEK2; JTK4; CD333; HSFGFR3EX |
Entrez GeneID | 2261 |
Swissprot | P22607 |
clone | 1E3F9 |
WB Predicted band size | 87.7kDa |
Host/Isotype | Mouse IgG2a |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30821

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