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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Mouse Monoclonal Antibody to FGFR3

  • 货号:

    30821
  • 别名:

    ACH; CEK2; JTK4; CD333; HSFGFR3EX
  • 产品上架时间:

    2024-01-01
  • 应用:

  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P22607
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to FGFR3

Description

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

References

1.Mol Cancer. 2013 Jul 31;12:83.

Specification

Aliases ACH; CEK2; JTK4; CD333; HSFGFR3EX
Entrez GeneID 2261
Swissprot P22607
clone 1E3F9
WB Predicted band size 87.7kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30821

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