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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunofluorescence analysis of HeLa cells using SIRT4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of HeLa cells using SIRT4 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to SIRT4

  • 货号:

    30850
  • 别名:

    SIR2L4
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9Y6E7
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to SIRT4

Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

References

1.Eur J Histochem. 2011 Mar 21;55(1):e10.
2.J Biol Chem. 2014 Feb 14;289(7):4135-44.

Specification

Aliases SIR2L4
Entrez GeneID 23409
Swissprot Q9Y6E7
clone 6G6D2
WB Predicted band size 35.2kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human SIRT4 (AA: 215-314) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/100 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000
XML 地图