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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P04179(PFN2 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
The image is immunohistochemistry of paraffin-embedded Human brain tissue using P04179(PFN2 Antibody) at dilution 1/30. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P04179(PFN2 Antibody) at dilution 1/30. (Original magnification: ×200)

Rabbit Polyclonal Antibody to PFN2

  • 货号:

    P04179
  • 别名:

    PFL, D3S1319E
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P35080
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to PFN2

Description

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Specification

Aliases PFL, D3S1319E
Swissprot P35080
WB Predicted band size 15 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human PFN2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/25-1/100
ELISA 1/1000-1/5000
XML 地图