SNX33 (sorting nexin-33), also known as SH3PX3, SH3PXD3C or SNX30, is a 574 amino acid protein that interacts with ADAM15 and FAS-L. Belonging to the sorting nexin family, SNX33 contains one BAR domain, one PX (phox homology) domain and one SH3 domain. The gene that encodes SNX33 consists of over 14,000 bases and maps to human chromosome 15q24.2. Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region.