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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse muscle tissue, Primary antibody: P05693(MAFA Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P05693(MAFA Antibody) at dilution 1/20. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P05693(MAFA Antibody) at dilution 1/20. (Original magnification: ×200)

Rabbit Polyclonal Antibody to MAFA

货号：
P05693
别名：
hMafA; RIPE3b1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q8NHW3
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to MAFA

Description
Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Description

Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Specification
Aliases	hMafA; RIPE3b1
Swissprot	Q8NHW3
WB Predicted band size	37 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human MAFA
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.