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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P05949(NF1 Antibody) at dilution 1/65. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P05949(NF1 Antibody) at dilution 1/65. (Original magnification: ×200)

Rabbit Polyclonal Antibody to NF1

货号：
P05949
别名：
WSS; NFNS; VRNF
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P21359
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to NF1

Description
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Description

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Specification
Aliases	WSS; NFNS; VRNF
Swissprot	P21359
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human NF1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.