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Mouse Monoclonal Antibody to CIRBP
-
货号:
31147 -
别名:
CIRP -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q14011 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to CIRBP
Description |
---|
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
References |
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1.Med Sci Monit. 2015 May 2;21:1256-60. 2.Int J Gynecol Pathol. 2003 Jul;22(3):240-7. |
Specification |
|
---|---|
Aliases | CIRP |
Entrez GeneID | 1153 |
Swissprot | Q14011 |
clone | 6E12B3 |
WB Predicted band size | 18.6kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CIRBP (AA: 1-90) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using CIRBP mouse mAb against SW480 (1), PC-3 (2), A431 (3), and U251 (4) cell lysate.
- Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CIRBP mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CIRBP mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31147

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