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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat and Raji cell lysates, Primary antibody: P07187(CDKN1B Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 seconds
The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P07187(CDKN1B Antibody) at dilution 1/50. (Original magnification: ×200)
HOT

Rabbit Polyclonal Antibody to CDKN1B

  • 货号:

    P07187
  • 别名:

    KIP1; MEN4; CDKN4; MEN1B; P27KIP1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P46527
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to CDKN1B

Description

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Specification

Aliases KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Swissprot P46527
WB Predicted band size 22 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human CDKN1B
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/50-1/100
ELISA 1/5000-1/10000
XML 地图