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Rabbit Polyclonal Antibody to RAF1
-
货号:
P07223 -
别名:
NS5; CRAF; Raf-1; c-Raf; CMD1NN -
应用:
WB,IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
P04049 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to RAF1
Description |
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This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. |
Specification |
|
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Aliases | NS5; CRAF; Raf-1; c-Raf; CMD1NN |
Swissprot | P04049 |
WB Predicted band size | 73 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human RAF1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
- Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse muscle tissue and Hepg2 cell, Primary antibody: P07223(RAF1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
- The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07223(RAF1 Antibody) at dilution 1/40. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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