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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD197 mouse mAb against C6 (1) cell lysate.
Flow cytometric analysis of HL-60 cells using CD197 mouse mAb (green) and negative control (red).
Flow cytometric analysis of K562 cells using CD197 mouse mAb (green) and negative control (red).
HOT

Mouse Monoclonal Antibody to CD197

  • 货号:

    31345
  • 别名:

    BLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P32248
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CD197

Description

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

References

1.Gastric Cancer. 2017 Mar;20(2):235-245.
2.J Surg Oncol. 2015 Jul;112(1):86-92.

Specification

Aliases BLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7
Entrez GeneID 1236
Swissprot P32248
clone 4B7B8
WB Predicted band size 42.9kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD197 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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