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Mouse Monoclonal Antibody to CD152
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货号:
31352 -
别名:
CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3 -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P16410 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to CD152
Description |
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This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
References |
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1.Asian Pac J Cancer Prev. 2016;17(8):3785-91. 2.Eur J Cancer. 2015 Nov;51(17):2689-97. |
Specification |
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Aliases | CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3 |
Entrez GeneID | 1493 |
Swissprot | P16410 |
clone | 8B3F8 |
WB Predicted band size | 24.6kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31352

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