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Rabbit Polyclonal Antibody to WEE2
-
货号:
P12878 -
别名:
OOMD5; WEE1B -
应用:
IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P0C1S8 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to WEE2
Description |
---|
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity). |
Specification |
|
---|---|
Aliases | OOMD5; WEE1B |
Swissprot | P0C1S8 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human WEE2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
- The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12878(WEE2 Antibody) at dilution 1/40. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P12878(WEE2 Antibody) at dilution 1/40. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P12878

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