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Western blot analysis of HEXIM1 in rat HEART lysates using HEXIM1 antibody.
Western blot analysis of HEXIM1 in NIH/3T3 lysates using HEXIM1 antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of HEXIM1 in theHeLa lysates using HEXIM1 antibody
Immunofluorescence analysis of HEXIM1 in HeLa using HEXIM1 antibody. The picture on the right is blocked using the synthesized peptide.
Rabbit Polyclonal Antibody to HEXIM1
-
货号：
P23155 -
别名：
CLP1; EDG1; HIS1; MAQ1 -
应用：
WB,IHC,IF -
反应种属：
Human,Mouse,Rat -
抗体类型：
Primary antibody -
Swissprot：
O94992 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to HEXIM1
Description |
|---|
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:14580347, PubMed:15713661, PubMed:15201869). In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:12832472, PubMed:14580347, PubMed:15713661, PubMed:15201869). May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity (PubMed:15940264, PubMed:15941832, PubMed:17088550). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). |
Specification |
|
|---|---|
| Aliases | CLP1; EDG1; HIS1; MAQ1 |
| Entrez GeneID | 10614 |
| Swissprot | O94992 |
| WB Predicted band size | Calculated MW: 41 kDa; Observed MW: 41 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HEXIM1. AA range:181-230 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| ELISA | 1/10000 |
Product Image
- Western blot analysis of HEXIM1 in rat HEART lysates using HEXIM1 antibody.
- Western blot analysis of HEXIM1 in NIH/3T3 lysates using HEXIM1 antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of HEXIM1 in theHeLa lysates using HEXIM1 antibody
- Immunofluorescence analysis of HEXIM1 in HeLa using HEXIM1 antibody. The picture on the right is blocked using the synthesized peptide.
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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