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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using MSH2 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3), and A431 (4) cell lysate.
Immunofluorescence analysis of Hela cells using MSH2 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Immunofluorescence analysis of Hela cells using MSH2 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Flow cytometric analysis of Hela cells using MSH2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using MSH2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using MSH2 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to MSH2

  • 货号:

    31797
  • 别名:

    FCC1; COCA1; HNPCC; LCFS2; hMSH2; HNPCC1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF,FCM
  • 反应种属:

    Human, Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P43246
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to MSH2

Description

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

References

1.Anticancer Res. 2018 May;38(5):2841-2848.
2.Clin Cancer Res. 2017 Nov 15;23(22):6863-6874.

Specification

Aliases FCC1; COCA1; HNPCC; LCFS2; hMSH2; HNPCC1
Entrez GeneID 4436
Swissprot P43246
clone 2E2C7
WB Predicted band size 104.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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