Description
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

References
English J.M., Vanderbilt C.A., Xu S., Marcus S., Cobb M.H.J. Biol. Chem. 270:28897-28902(1995)

Specification
Aliases	Map2k5
Entrez GeneID	29568;
Swissprot	Q62862
WB Predicted band size	46kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S(p)I-A-K-T(p)-Y-V) derived from Rat MEK5.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000