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Rabbit Polyclonal Antibody to FAK (Phospho-Tyr576)
-
货号:
P40593 -
别名:
FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK -
应用:
WB -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q05397 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Polyclonal Antibody to FAK (Phospho-Tyr576)
Description |
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Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
References |
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Tong L, et al. (2013)Biochim Biophys Acta 1833, 1304-15. Chen S, et al. (2013)Sci Signal 6, ra40. Tian H, et al. (2012)EMBO J 31, 3885-900. |
Specification |
|
---|---|
Aliases | FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK |
Entrez GeneID | 5747; |
Swissprot | Q05397 |
WB Predicted band size | 125kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of Tyrosine576 (S-T-Y(p)-Y-K) derived from Human FAK. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/1000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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