Description
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation

References
Hong S, et al. (2014) J Biol Chem Puustinen P, et al. (2014) CJ Cell Biol 204, 713-27 Martineau Y, et al. (2014) Mol Cell Biol 34, 1046-53

Specification
Aliases	KS6B1; P70-S6K; RPS6KB1; Ribosomal protein S6 kinase; polypeptide 1
Entrez GeneID	6198;
Swissprot	P23443
WB Predicted band size	70kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine389/412(G-F-T(p)-Y-V) derived from Human p70 S6 Kinase .
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000