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Western blot analysis of extracts from K562 tissue using Epo-R (Phospho-Tyr368) antibody P40626.The lane on the right is treated with the antigen-specific peptide.
Rabbit Polyclonal Antibody to Epo-R (Phospho-Tyr368)
-
货号：
P40626 -
别名：
EPO R; EPO-R; epor; -
应用：
WB -
反应种属：
Human,Mouse -
抗体类型：
Primary antibody -
Swissprot：
P19235 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to Epo-R (Phospho-Tyr368)
Description |
|---|
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307 Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97 Zhang YL, et al. (2009) Mol Cell 33, 266-74 |
Specification |
|
|---|---|
| Aliases | EPO R; EPO-R; epor; |
| Entrez GeneID | 2057; |
| Swissprot | P19235 |
| WB Predicted band size | 55kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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