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Western blot analysis of extracts from Rat heart tissue using Caldesmon (Phospho-Ser789) Antibody P40641.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to Caldesmon (Phospho-Ser789)

  • 货号:

    P40641
  • 别名:

    CDM, HCAD, LCAD, H-CAD, L-CAD
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q05682
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to Caldesmon (Phospho-Ser789)

Description

Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration

Specification

Aliases CDM, HCAD, LCAD, H-CAD, L-CAD
Entrez GeneID 800;
Swissprot Q05682
WB Predicted band size 80kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of serine 789 (V-T-S(p)-P-T) derived from Human Caldesmon.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40641

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