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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using HDAC1 mouse mAb against Hela (1), Raw264.7 (2), K562 (3), and Jurkat (4) cell lysate.

Immunofluorescence analysis of Hela cells using HDAC1 mouse mAb (green). Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis of Hela cells using HDAC1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using HDAC1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human colon tissues using HDAC1 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using HDAC1 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to HDAC1

货号：
32103
别名：
HD1; RPD3; KDAC1; GON-10; RPD3L1
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q13547
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to HDAC1

Description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

References
1.Cell Commun Signal. 2019 Jul 29;17(1):86. 2.Hum Pathol. 2019 Mar;85:194-201.

Specification
Aliases	HD1; RPD3; KDAC1; GON-10; RPD3L1
Entrez GeneID	3065
Swissprot	Q13547
clone	2A1D3
WB Predicted band size	55.1kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Purified recombinant fragment of human HDAC1 (AA: 321-482) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide