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Western blot analysis of extracts from 3T3 cells, treated with EGF (200ng/ml, 30mins), using Proteasome α3 (Phospho-Ser250) antibody P40718. The lane on the right is treated with the synthesized peptide.

Rabbit Polyclonal Antibody to Proteasome α3 (Phospho-Ser250)

货号：
P40718
别名：
EC 3.4.25.1; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; proteasome component C8; Proteasome subunit alpha type 3; PSA3; PSC8
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P25788
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to Proteasome α3 (Phospho-Ser250)

Description
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

Description

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

Specification
Aliases	EC 3.4.25.1; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; proteasome component C8; Proteasome subunit alpha type 3; PSA3; PSC8
Entrez GeneID	5684;
Swissprot	P25788
WB Predicted band size	32kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 250 (D-E-S(p)-D-D) derived from Human Proteasome α3.
Formulation	Purified antibody in PBS with 0.05% sodium azide.