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Western blot analysis of extracts from HeLa cells, treated with calyculinA (50ng/ml, 30mins), using MDM4 (Phospho-Ser367) antibody P40746. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using MDM4 (Phospho-Ser367) antibody P40746. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal Antibody to MDM4 (Phospho-Ser367)

货号：
P40746
别名：
double minute 4 protein; Mdm2-like p53-binding protein; MDMX; p53-binding protein Mdm4
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O15151
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to MDM4 (Phospho-Ser367)

Description
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Specification
Aliases	double minute 4 protein; Mdm2-like p53-binding protein; MDMX; p53-binding protein Mdm4
Entrez GeneID	4194;
Swissprot	O15151
WB Predicted band size	80kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4.
Formulation	Purified antibody in PBS with 0.05% sodium azide.