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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).
Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human tonsil tissues using GZMK mouse mAb with DAB staining.

Mouse Monoclonal Antibody to GZMK

  • 货号:

    32147
  • 别名:

    TRYP2
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P49863
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to GZMK

Description

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

References

1,Brain. 2019 Nov 1;142(11):3411-3427.
2,J Invest Dermatol. 2019 Apr;139(4):930-939.

Specification

Aliases TRYP2
Entrez GeneID 3003
Swissprot P49863
clone 5B4A5
WB Predicted band size 29kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
XML 地图