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Rabbit Polyclonal Antibody to FAK(Ab-861)
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货号:
P41303 -
别名:
FADK 1; FAK1; PTK2 -
产品上架时间:
2024-01-01 -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q05397 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to FAK(Ab-861)
Description |
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Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
References |
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Shi Q, et al. (2003) Mol Biol Cell; 14(10): 4306-15.Vadlamudi RK, et al. (2003) FEBS Lett; 543(1-3): 76-80.Eliceiri BP, et al. (2002) J Cell Biol Apr 01; 157(1): 149-60.Abu-Ghazaleh R, (2001) et al. Biochem J; 360(Pt 1): 255-64.Slack JK, et al.(2001) Oncogene; 20(10): 1152-63. |
Specification |
|
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Aliases | FADK 1; FAK1; PTK2 |
Entrez GeneID | 5747; |
Swissprot | Q05397 |
WB Predicted band size | 125kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around aa. 859~863 (H-I-Y-Q-P) derived from Human FAK. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P41303

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