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Western blot analysis of extracts from 293 cells using G3BP-1(Ab-232) Antibody P41324 and the same antibody preincubated with blocking peptide.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using G3BP-1(Ab-232) Antibody P41324(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to G3BP-1(Ab-232)

货号：
P41324
别名：
G3BP; GAP SH3-domain binding protein 1;
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13283
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to G3BP-1(Ab-232)

Description
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Description

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

References
Tao WA, et al. (2005) Nat Methods. 2 (8): 591-598.Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.Beausoleil SA, et al. (2004) Proc Natl Acad Sci USA.101 (33): 12130-12135.Tourrihre H, et al. (2003) J Cell Biol.160 (6): 823-831.

Specification
Aliases	G3BP; GAP SH3-domain binding protein 1;
Entrez GeneID	10146;
Swissprot	Q13283
WB Predicted band size	60kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.230~234 (S-S-S-P-A) derived from Human G3BP-1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.