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Western blot analysis of extracts from 293 and Hela cells using ASK1(Ab-966) Antibody P41350.

Immunofluorescence staining of methanol-fixed Hela cells using ASK1(Ab-966) Antibody P41350.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ASK1(Ab-966) Antibody P41350(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to ASK1(Ab-966)

货号：
P41350
别名：
ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q99683
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to ASK1(Ab-966)

Description
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

References
Zhang W, et al. (2005) J Biol Chem. 280(19): 19036-19044. Fujii K, et al. (2004) Oncogene. 23(29):5099-5104. Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12; 279(11): 10442-10449. Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96(15): 8511-8515.

Specification
Aliases	ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5
Entrez GeneID	4217;
Swissprot	Q99683
WB Predicted band size	155kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.964~968 (S-I-S-L-P) derived from Human ASK1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.