Description
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

References
Zhou R, et al. (2005) J Cell Sci: 118 (Pt 19): 4381-91.Shiue H, et al.(2005) J Biol Chem: 280(2): 1688-95.Zhao H, et al. (2004) Proc Natl Acad Sci U S A: 101(25): 9485-90.Fievet BT, et al. (2004) J Cell Biol: 164(5): 653-9.

Specification
Aliases	Cytovillin; EZRI; VIL2; Villin 2; p81
Entrez GeneID	7430;
Swissprot	P15311
WB Predicted band size	81kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa. 565~569 (Y-K-T-L-R) derived from Human Ezrin.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000