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Western blot analysis of extracts from 293 cells using MEK1/MEK2(Ab-217/221) Antibody P41407 and the same antibody preincubated with blocking peptide.
Immunofluorescence staining of methanol-fixed Hela cells using MEK1/MEK2(Ab-217/221) Antibody P41407.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using MEK1/MEK2(Ab-217/221) Antibody P41407(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to MEK1/MEK2(Ab-217/221)

  • 货号:

    P41407
  • 别名:

    ERK activator kinase 1/ERK activator kinase2; MAP kinase kinase 1/MAP kinase kinase 2; MAP2K1/MAP2K1; MAPK/ERK kinase 1/MAPK/ERK kinase 2; MAPKK 1/MAPKK 1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q02750
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to MEK1/MEK2(Ab-217/221)

Description

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

References

Shen R, et al. (2002) Mol Cell Biol; 22(10): 3230-3236Preisinger C, et al. (2005) EMBO J; 24(4): 753-765Laine P, et al. (2000) Biochem J; 349(Pt 1): 19-25Yaglom J, et al. (2003) Mol Cell Biol; 23(11): 3813-3824Dahan S, et al. (2002) Infect Immun; 70(5): 2304-2310

Specification

Aliases ERK activator kinase 1/ERK activator kinase2; MAP kinase kinase 1/MAP kinase kinase 2; MAP2K1/MAP2K1; MAPK/ERK kinase 1/MAPK/ERK kinase 2; MAPKK 1/MAPKK 1
Entrez GeneID 5604;
Swissprot Q02750
WB Predicted band size 45kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa.215~219/219~223 (I-D-S-M-A) derived from Human MEK1/MEK2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200
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