Description
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

References
von Sengbusch A, et al. (2005) Am J Pathol ; 166(2): 585-596 Fornaro M, et al. (2000) Mol Biol Cell ; 11(7): 2235-2249 Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96(16): 9021-9026.

Specification
Aliases	FADK; PTK2; FAK1; FRNK; PTK2
Entrez GeneID	5747;
Swissprot	Q05397
WB Predicted band size	125kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from Human FAK.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000