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Western blot analysis of extracts from Jurkat cells using p62Dok(Ab-362) Antibody P41461 and the same antibody preincubated with blocking peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok(Ab-362) Antibody P41461(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p62Dok(Ab-362)

  • 货号:

    P41461
  • 别名:

    DOK1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q99704
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to p62Dok(Ab-362)

Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

References

Zhou Songyang, et,al. (2001) J. Biol. Chem ; 276: 2459 - 2465.Jean-Guy N

Specification

Aliases DOK1
Entrez GeneID 1796;
Swissprot Q99704
WB Predicted band size 62kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.360~364 (P-I-Y-D-E) derived from Human p62Dok.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41461

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