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Western blot analysis of extracts from PC12 cells using Melanoma-associated antigen D1 Antibody P41517 and the same antibody preincubated with blocking peptide.

Rabbit Polyclonal Antibody to Melanoma-associated antigen D1

  • 货号:

    P41517
  • 别名:

    MAGED1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9QYH6
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to Melanoma-associated antigen D1

Description

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

References

Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20. Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31. Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.

Specification

Aliases MAGED1
Entrez GeneID 94275;
Swissprot Q9QYH6
WB Predicted band size 95kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41517

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