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Western blot analysis of extracts from 293T,DU145,SKOV3 and HT29 cells using DLC1 (Ab-868) Antibody P41603.
Rabbit Polyclonal Antibody to DLC1 (Ab-868)
-
货号：
P41603 -
别名：
ARHGAP7; KIAA1723; STARD12 -
应用：
WB -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q96QB1 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to DLC1 (Ab-868)
Description |
|---|
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. |
References |
|---|
| 1)protein DLC-1 on cell morphology and migration."Kim T.Y., Healy K.D., Der C.J., Sciaky N., Bang Y.J., Juliano R.L.J. Biol. Chem. 283:32762-32770(2008) 2)Kawai K., Iwamae Y., Yamaga M., Kiyota M., Ishii H., Hirata H., Homma Y., Yagisawa H.Genes Cells 14:227-241(2009) 3)Erlmann P., Schmid S., Horenkamp F.A., Geyer M., Pomorski T.G., Olayioye M.A.Mol. Biol. Cell 20:4400-4411(2009) |
Specification |
|
|---|---|
| Aliases | ARHGAP7; KIAA1723; STARD12 |
| Entrez GeneID | 10395; |
| Swissprot | Q96QB1 |
| WB Predicted band size | 171, 127, 123, 114kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.866~870 (R-N-S-S-S) derived from Human DLC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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