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Western blot analysis of extracts from NIH/3T3 cells, using p130 Cas (Ab-410) antibody P41637.
Western blot analysis of extracts from HuvEc cells using p130 Cas (Ab-410) antibody P41637. The lane on the left is treated with synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p130 Cas (Ab-410) antibody P41637.

Rabbit Polyclonal Antibody to p13Cas (Ab-410)

  • 货号:

    P41637
  • 别名:

    BCAR1; Breast cancer anti-estrogen resistance 1; CRK-ASSOCIATED SUBSTRATE; CRKAS;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P56945
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to p13Cas (Ab-410)

Description

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535.Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863.Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189.Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6

Specification

Aliases BCAR1; Breast cancer anti-estrogen resistance 1; CRK-ASSOCIATED SUBSTRATE; CRKAS;
Entrez GeneID 9564;
Swissprot P56945
WB Predicted band size 130kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized non-phosphopeptide derived from human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-T-A-V).
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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