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Western blot analysis of extracts from COS7 cells treated with EGF (200ng/ml, 30min), using PLCG1 (Ab-771) antibody P41638.

Western blot analysis of extracts from COS7 cells (Lane 2), and JK cells (Lane 3), using PLCG1 (Ab-771) antiobdy P41638. The lane on the left is treated with synthesized peptide.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLCG1 (Ab-771) antibody P41638.

Rabbit Polyclonal Antibody to PLCG1 (Ab-771)

货号：
P41638
别名：
Phospholipase C gamma 1; PLC148; PHOSPHOLIPASE C-148;
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P19174
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PLCG1 (Ab-771)

Description
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.Denis Tvorogov, J. Cell Sci., Feb 2005; 118: 601 - 610.Brenda J. Irvin, Mol. Cell. Biol., Dec 2000; 20: 9149 - 9161.Benoit Poulin, J. Biol. Chem., Feb 2000; 275: 6411.Ichiro Nakamura, J. Cell Biol., Jan 2001; 152: 361.

Description

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.Denis Tvorogov, J. Cell Sci., Feb 2005; 118: 601 - 610.Brenda J. Irvin, Mol. Cell. Biol., Dec 2000; 20: 9149 - 9161.Benoit Poulin, J. Biol. Chem., Feb 2000; 275: 6411.Ichiro Nakamura, J. Cell Biol., Jan 2001; 152: 361.

Specification
Aliases	Phospholipase C gamma 1; PLC148; PHOSPHOLIPASE C-148;
Entrez GeneID	5335;
Swissprot	P19174
WB Predicted band size	150kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized non-phosphopeptide derived from human PLCG1 around the phosphorylation site of tyrosine 771 (P-D-Y-G-A).
Formulation	Purified antibody in PBS with 0.05% sodium azide.