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Western blot analysis of extracts from HeLa cells, treated with UV, using CREB (Ab-133) antibody P41689.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CREB (Ab-133) antibody P41689.
Rabbit Polyclonal Antibody to CREB (Ab-129/133)
-
货号：
P41689 -
别名：
cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1; -
应用：
WB,IHC -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P16220 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to CREB (Ab-129/133)
Description |
|---|
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55.Tan Y, et al.( 1996) EMBO J; 15(17): 4629-42.Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385.Mayo LD, et al. (2001) Biol Chem; 276(27): 25184-9.Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-59 |
Specification |
|
|---|---|
| Aliases | cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1; |
| Entrez GeneID | 1385; |
| Swissprot | P16220 |
| WB Predicted band size | 43kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 or serine 133(S-R-R-P-S). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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