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Western blot analysis of extracts from 293 cells, treated with insulin (0.01U/ml, 15mins), using B-RAF (Ab-446) antibody P41706.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using B-RAF (Ab-446) antibody P41706.

Rabbit Polyclonal Antibody to B-RAF (Ab-446)

  • 货号:

    P41706
  • 别名:

    B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P15056
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to B-RAF (Ab-446)

Description

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003)

Specification

Aliases B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1
Entrez GeneID 673;
Swissprot P15056
WB Predicted band size 84kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D).
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41706

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