Description
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Bechtel S., BMC Genomics 8:399-399(2007).

Specification
Aliases	p53-binding protein 1; P531; TP53B; TP53BP1; TRP53BP1
Entrez GeneID	7158;
Swissprot	Q12888
WB Predicted band size	170kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from Internal of human 53BP1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000