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Western blot analysis of extracts from NIH-3T3 cells, using GRK2 (Ab-86) antibody P41771.

Western blot analysis of extracts from cos-7 cells (Lane 2), using GRK2 (Ab-86) antiobdy P41771. The lane on the left is treated with synthesized peptide.

Rabbit Polyclonal Antibody to GRK2 (Ab-86)

货号：
P41771
别名：
ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P25098
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to GRK2 (Ab-86)

Description
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Benovic J.L., FEBS Lett. 283:122-126(1991).Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994).

Description

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Benovic J.L., FEBS Lett. 283:122-126(1991).Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994).

Specification
Aliases	ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1
Entrez GeneID	156;
Swissprot	P25098
WB Predicted band size	80kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from N-terminal of human ADRBK1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.