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Western blot analysis of extracts from COLO205 cells, using XPA antibody P41849.
Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy P41849. The lane on the left is treated with systhesized peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody P41849.

Rabbit Polyclonal Antibody to XPA

  • 货号:

    P41849
  • 别名:

    DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P23025
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to XPA

Description

Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183. Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619. Karen M. Vasquez, PNAS, Apr 2002; 99: 5848.

Specification

Aliases DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein;
Entrez GeneID 7507;
Swissprot P23025
WB Predicted band size 40kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from Internal of human XPA.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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