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Rabbit Polyclonal Antibody to XPA
-
货号:
P41849 -
别名:
DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein; -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P23025 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to XPA
Description |
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Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183. Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619. Karen M. Vasquez, PNAS, Apr 2002; 99: 5848. |
Specification |
|
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Aliases | DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein; |
Entrez GeneID | 7507; |
Swissprot | P23025 |
WB Predicted band size | 40kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from Internal of human XPA. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
Product Image
- Western blot analysis of extracts from COLO205 cells, using XPA antibody P41849.
- Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy P41849. The lane on the left is treated with systhesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody P41849.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P41849

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