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Immunohistochemistry analysis of paraffin-embedded human brain tissue using CTRO antibody P41859.

Rabbit Polyclonal Antibody to CTRO

  • 货号:

    P41859
  • 别名:

    Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O14578
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to CTRO

Description

Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.Nagase T., DNA Res. 6:63-70(1999).Scherer S.E., Nature 440:346-351(2006).Gruneberg U., J. Cell Biol. 172:363-372(2006).

Specification

Aliases Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT
Entrez GeneID 11113;
Swissprot O14578
WB Predicted band size 231kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human CTRO.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41859

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