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Rabbit Polyclonal Antibody to CTRO
-
货号:
P41859 -
别名:
Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT -
应用:
IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O14578 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to CTRO
Description |
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Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.Nagase T., DNA Res. 6:63-70(1999).Scherer S.E., Nature 440:346-351(2006).Gruneberg U., J. Cell Biol. 172:363-372(2006). |
Specification |
|
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Aliases | Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT |
Entrez GeneID | 11113; |
Swissprot | O14578 |
WB Predicted band size | 231kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human CTRO. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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IHC | 1/50-1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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