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Western blot analysis of extracts from HT-29 cells, using CLK4 antibody P42111.

Rabbit Polyclonal Antibody to CLK4

  • 货号:

    P42111
  • 别名:

    Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9HAZ1
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to CLK4

Description

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Schultz J., Genomics 71:368-370(2001).McNally T., Protein Sci. 12:1562-1566(2003).Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003).

Specification

Aliases Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4;
Entrez GeneID 57396;
Swissprot Q9HAZ1
WB Predicted band size 65kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human CLK4.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42111

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