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Immunofluorescence analysis of LOVO cells, using DCC antibody P42205.
Rabbit Polyclonal Antibody to DCC
-
货号：
P42205 -
别名：
colorectal cancer suppressor; deleted in colorectal carcinoma; netrin receptor DCC; tumor suppressor protein DCC; -
应用：
IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P43146 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to DCC
Description |
|---|
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.Hedrick L., Genes Dev. 8:1174-1183(1994).Cho K.R., Genomics 19:525-531(1994).Sjoeblom T., Science 314:268-274(2006). |
Specification |
|
|---|---|
| Aliases | colorectal cancer suppressor; deleted in colorectal carcinoma; netrin receptor DCC; tumor suppressor protein DCC; |
| Entrez GeneID | 1630; |
| Swissprot | P43146 |
| WB Predicted band size | 158kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human DCC. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IF | 1/100-1/500 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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