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Western blot analysis of extracts from HuvEc cells, using HSD11B1 antibody P42374.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HSD11B1 antibody P42374.

Rabbit Polyclonal Antibody to HSD11B1

  • 货号:

    P42374
  • 别名:

    Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-DH; 11-beta-hydroxysteroid;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P28845
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to HSD11B1

Description

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol By similarity.Tannin G.M., J. Biol. Chem. 266:16653-16658(1991).Draper N., J. Clin. Endocrinol. Metab. 87:4984-4990(2002).Ota T., Nat. Genet. 36:40-45(2004) .

Specification

Aliases Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-DH; 11-beta-hydroxysteroid;
Entrez GeneID 3290;
Swissprot P28845
WB Predicted band size 32kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from N-terminal of human HSD11B1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42374

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