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Western blot analysis of extracts from LOVO cells, HepG2 cells and K562 cells, using RAD18 antibody P42395.

Rabbit Polyclonal Antibody to RAD18

  • 货号:

    P42395
  • 别名:

    E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; Postreplication repair protein RAD18
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9NS91
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to RAD18

Description

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).Xin H., Nucleic Acids Res. 28:2847-2854(2000).Muzny D.M., Nature 440:1194-1198(2006).

Specification

Aliases E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; Postreplication repair protein RAD18
Entrez GeneID 56852;
Swissprot Q9NS91
WB Predicted band size 56kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human RAD18.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42395

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