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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using EDN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using EDN1 mouse mAb (green) and negative control (red).

Flow cytometric analysis of HepG2 cells using EDN1 mouse mAb (green) and negative control (red).

Flow cytometric analysis of NIH3T3 cells using EDN1 mouse mAb (green) and negative control (red).

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Mouse Monoclonal Antibody to EDN1

货号：
32283
别名：
ET1; QME; PPET1; ARCND3; HDLCQ7
产品上架时间：
2024-01-01
应用：
IF,FCM
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
P05305
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to EDN1

Description
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Description

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

References
1，BMC Res Notes. 2021 May 19;14(1):194. 2，Respir Res. 2021 May 13;22(1):148.

Specification
Aliases	ET1; QME; PPET1; ARCND3; HDLCQ7
Entrez GeneID	1906
Swissprot	P05305
clone	4E6E5
WB Predicted band size	24.4KDa
Host/Isotype	Mouse IgG2a
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide